Whether for recreational or therapeutic uses, Kratom has become a phenomenon in the United States in recent years in Europe. Kratom is the common name for the dry leaves of the tropical deciduous shrub Mitragyna speciosa.

This member of the coffee family comes from several Southeast Asian countries, especially Thailand and Indonesia. Indigenous peoples have used this herb for centuries as a drug, recreational substance and physical stimulant. Traditionally, Thai workers chewed fresh leaves to stimulate themselves during physical labor and to improve their mood during more monotonous tasks. The working of the kratom is great to have the desired results. There is improvisation in the moods and skills of the individuals. The results are the excellent one when you select the right product. The performing of the tasks is great with the products.


Kratom contains more than 25 different active compounds, including the alkaloids Raubasin, Corinantine, Cataquine, Mitrafillin, and Mitraginine. The main active alkaloids are Mitraginine and 7-Hydroxymitraginine.

These two alkaloids are opioids and adrenergic receptor agonists. At low doses, they act as stimulants with a predominant adrenergic effect. And with higher doses, they have a sedative effect. The different types of Kratom have different effects due to the unique alkaloid profile of each of the subspecies.


Kratom tolerance can develop, especially in regular consumers. Like any other substance, the body becomes accustomed to its consumption and creates some tolerance. The brain is great at adapting; Reduces its activity by making its own chemicals compensate for the external introduction of other compounds, in order to keep things in homeostasis or equilibrium. The consumer experiences this as tolerance.

Tolerance can lead to increased dosage to achieve desired effects. This continuing consumption trend encourages numbing and overuse, and over time could lead to addiction.

What to do when kratom stops working? There is no magic solution to avoid Kratom’s tolerance, but several things can be done.

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It is important to avoid the “stagnant variety syndrome”. This condition occurs when the same species is taken over an extended period of time. The intake of the same variety or mixture of varieties develops tolerance much faster. Therefore, it is best to have several types of Kratom and mix them frequently, alternating doses and varieties. In this way, the level of agonists will not reach a stable concentration in the brain and tolerance will be less likely to occur.


People who consume Kratom excessively should take a break for the brain to rest and readjust.

They will have to reduce their intake to a quarter of the usual daily dose, or even abstain completely for a while. The longer you spend between intakes, the faster the tolerance will be removed.

To end a high tolerance, you must abstain for at least 2 months. After this period of abstinence, it could be rapidly developed again. If so, a longer abstinence period is needed.


Tolerance must be prevented from the beginning. If you consume Kratom as part of your health care, try to limit the doses to one a day. A large dose is better than several small ones. If you consume it as a recreational experience, try using it only two or three times a week. The body will have time to regulate its brain chemistry and thus prevent the development of tolerance.

Novices should consume Kratom as powders and avoid concentrates since the brain adapts very quickly to high doses and tolerance develops rapidly.